[The treatment of pulmonary tuberculosis in a special hospital. Its evolution from 1948 to 1986]. / Tratamiento de la tuberculosis pulmonar en un hospital monográfico. Evolución desde 1948 a 1986.

Nine hundred and sixty six patients diagnosed of pulmonary and/or pleural tuberculosis and admitted to a specialized hospital from 1948 to 1986, have been retrospectively analyzed, investigating their treatment and evolution. Sixty two percent of patients did not fulfil pharmaceutical treatment as far as number and dose of drugs, evolving through the decades (50, 60, 70, and 80s) with a 100%, 82%, 37% and 3% respectively. A 13% of patients did not receive any chemotherapy, 16% underwent surgery, and 53% received a second treatment. Real or hidden monotherapy was given to 38% of patients. Isoniazide has been the most uniformly used drug. Streptomycin has been the most frequently underdosed used drug. Sputum culture turned negative in 42% and 51% of patients during the first 3 and 6 months respectively, with a 42% of positives persisting after one year and a 30% when discharged. A statistically significant difference is observed when comparing all the variables between admitted patients up to 1969 and from 69 to 86 in favor of the second period.

[Evolution of pulmonary tuberculosis at a specialized hospital from its beginning to the present time. General aspects]. / Evolución de la tuberculosis pulmonar en un hospital monográfico desde su puesta en marcha hasta el momento actual. Aspectos generales.

A retrospective analysis of pleuropulmonary tuberculosis patients admitted to a specialized hospital from the day it started functioning to 1986 is performed. The epidemiological and clinical aspects of 966 medical histories are reviewed. 32% of these patients had household contacts with patients suffering the same disease. We could also observe an increase with time in the percentage of diabetic and alcoholic patients. With respect to the bacteriological study we have to point out that in 86% of patients Koch Bacillus was detected. A decrease in length of hospital stay as well as a decrease in mortality up to 3% is observed. These variables are recorded at two time points: when the hospital first started and at the present time, analyzing any possible statistically significant differences.